Ever wondered what the cellular trajectory is of a cancer cell metastasizing to the liver? Maria finished a tour de force @Cancer Research, mapping shapeshifting cancer stem cell phenotypes with high precision during metastasis formation.
Ooh…, regarding epithelial self-organization in organoids: it is conserved between mice, human, normal and cancer organoids. Its clinical relevance: the exact same processes take place during liver metastasis formation in patients.