We developed and validated a synthetic enhancer/promoter element that provides specific transcriptional activity in intestinal stem cells. The reporter, called STAR, is a user-friendly system to monitor and manipulate stem cells in human organoids. Among others, we documented that cell fate plasticity in tumors is an inherited trait from normal cells, rather than acquired by specific cancer mutations.
Hugo received new funding from KWF (€820k), the Dutch Cancer Foundation, to strengthen our team with two new PhD students. We will use this support to make a deep dive into the tumor microenvironment of Read more…
Hugo received a prestigious ERC consolidator grant (€2,0M) from the EU in support of our studies to understand the evolution of the tumor genome during the earliest formation of colon cancer. The project will rely Read more…
Beautiful ceremony in the Amsterdam Stedelijk Museum for modern art. AMMODO Science Award is a biannual prize for early-career scientists to continue their research line as they seem fit (€350k). Proud to be listed among Read more…
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